We All Live in a Virtual Submarine

Our seas and oceans hide a plethora of archaeological sites such as ancient shipwrecks that, over time, are being destroyed through activities such as deepwater trawling and treasure hunting. In 2006, a multidisciplinary team of 11 European institutions established the Venus (Virtual Exploration of Underwater Sites) consortium to make underwater sites more accessible by generating thorough, exhaustive 3D records for virtual exploration

Virtual Exploration of Underwater Archaeological Sites : Visualization and Interaction in Mixed Reality Environments

This paper describes the ongoing developments in Photogrammetry and Mixed Reality for the Venus European project (Virtual ExploratioN of Underwater Sites, http://www.venus-project.eu). The main goal of the project is to provide archaeologists and the general public with virtual and augmented reality tools for exploring and studying deep underwater archaeological sites out of reach of divers. These sites have to be reconstructed in terms of environment (seabed) and content (artifacts) by performing bathymetric and photogrammetric surveys on the real site and matching points between geolocalized pictures. The base idea behind using Mixed Reality techniques is to offer archaeologists and general public new insights on the reconstructed archaeological sites allowing archaeologists to study directly from within the virtual site and allowing the general public to immersively explore a realistic reconstruction of the sites. Both activities are based on the same VR engine but drastically differ in the way they present information. General public activities emphasize the visually and auditory realistic aspect of the reconstruction while archaeologists activities emphasize functional aspects focused on the cargo study rather than realism which leads to the development of two parallel VR demonstrators. This paper will focus on several key points developed for the reconstruction process as well as both VR demonstrators (archaeological and general public) issues. The ?rst developed key point concerns the densi?cation of seabed points obtained through photogrammetry in order to obtain high quality terrain reproduction. The second point concerns the development of the Virtual and Augmented Reality (VR/AR) demonstrators for archaeologists designed to exploit the results of the photogrammetric reconstruction. And the third point concerns the development of the VR demonstrator for general public aimed at creating awareness of both the artifacts that were found and of the process with which they were discovered by recreating the dive process from ship to seabed

We All Live in a Virtual Submarine

Our seas and oceans hide a plethora of archaeological sites such as ancient shipwrecks that, over time, are being destroyed through activities such as deepwater trawling and treasure hunting. In 2006, a multidisciplinary team of 11 European institutions established the Venus (Virtual Exploration of Underwater Sites) consortium to make underwater sites more accessible by generating thorough, exhaustive 3D records for virtual exploration. Over the past three years, we surveyed several shipwrecks around Europe and investigated advanced techniques for data acquisition using both autonomous and remotely operated vehicles coupled with innovative sonar and photogrammetric equipment. Access to most underwater sites can be difficult and hazardous owing to deep waters. However, this same inhospitable environment of ers extraordinary opportunities to archaeologists because darkness, low temperatures, and low oxygen rates are all favorable to preservation. From a visualization pipeline perspective, this project had two main challenges. First, we had to gather large amounts of raw data from various sources. Then, we had to develop techniques to filter, calibrate, and map the data and then bring it all together into a single accurate visual representation

Identifying nonlinear wave interactions in plasmas using two-point measurements: a case study of Short Large Amplitude Magnetic Structures (SLAMS)

A framework is described for estimating Linear growth rates and spectral energy transfers in turbulent wave-fields using two-point measurements. This approach, which is based on Volterra series, is applied to dual satellite data gathered in the vicinity of the Earth's bow shock, where Short Large Amplitude Magnetic Structures (SLAMS) supposedly play a leading role. The analysis attests the dynamic evolution of the SLAMS and reveals an energy cascade toward high-frequency waves.Comment: 26 pages, 13 figure

PRAD1 (Cyclin D1): A Parathyroid Neoplasia Gene on 11q13

Hyperparathyroidism is a central component of multiple endocrine neoplasia type 1 (MEN 1), and both sporadic and familial forms of parathyroid disease may share certain pathogenetic features. We recently identified a gene that is clonally rearranged with the PTH locus in a subset of sporadic parathyroid adenomas. This candidate oncogene, PRAD1 (previously D11S287), appears to contribute to parathyroid tumorigenesis in a fashion analogous to activation of C-MYC or BCL-2 by rearrangement with tissue-specific enhancers of the immunoglobulin genes in B-lymphoid neoplasia. The PRAD1 gene maps to 11q13 and has been linked to the BCL-1 breakpoint locus, although not to the most tightly linked MEN 1 markers, by pulsed field gel electrophoresis. PRAD1 may, in fact, be the long-sought BCL-1 lymphoma oncogene. PRAD1 encodes a novel type of cyclin protein and thus may normally function in controlling the cell cycle, perhaps through direct interaction with cdc2 or a related kinase. PRAD1\u27s possible primary, or more likely secondary, involvement in the pathogenesis of MEN 1-related tumors is unknown and under investigation

Modeling the viscosity of silicate melts containing manganese oxide

Our recently developed model for the viscosity of silicate melts is applied to describe and predict the viscosities of oxide melts containing manganese oxide. The model requires three pairs of adjustable parameters that describe the viscosities in three systems: pure MnO, MnO–SiO2 and MnO–Al2O3–iO2. The viscosity of other ternary and multicomponent silicate melts containing MnO is then predicted by the model without any additional adjustable model parameters. Experimental viscosity data are reviewed for melts formed by MnO with SiO2, Al2O3, CaO, MgO, PbO, Na2O and K2O. The deviation of the available experimental data from the viscosities predicted by the model is shown to be within experimental error limit

Whistler Wave Observations by \textit{Parker Solar Probe} During Encounter 11: Counter-Propagating Whistlers Collocated with Magnetic Field Inhomogeneities and their Application to Electric Field Measurement Calibration

Observations of the young solar wind by the Parker Solar Probe (PSP) mission reveal the existence of intense plasma wave bursts with frequencies between $0.05$ -- $0.20 f_\mathrm{ce}$ (tens of Hz up to ${\sim}300$ Hz) in the spacecraft frame. The wave bursts are often collocated with inhomogeneities in the solar wind magnetic field, such as local dips in magnitude or sudden directional changes. The observed waves are identified as electromagnetic whistler waves that propagate either sunward, anti-sunward, or in counter-propagating configurations during different burst events. Being generated in the solar wind flow the waves experience significant Doppler down-shift and up-shift {of wave frequency} in the spacecraft frame for sunward and anti-sunward waves, respectively. Their peak amplitudes can be larger than $2$~nT, where such values represent up to $10\%$ of the background magnetic field during the interval of study. The amplitude is maximum for propagation parallel to the background magnetic field. We (i) evaluate the properties of these waves by reconstructing their parameters in the plasma frame, (ii) estimate the effective length of the PSP electric field antennas at whistler frequencies, and (iii) discuss the generation mechanism of these waves

Fibrinogen splice variation and cross-linking: Effects on fibrin structure/function and role of fibrinogen γ’ as thrombomobulin II

Fibrin is an important matrix protein that provides the backbone to the blood clot, promoting tissue repair and wound healing. Its precursor fibrinogen is one of the most heterogenous proteins, with an estimated 1 million different forms due to alterations in glycosylation, oxidation, single nucleotide polymorphisms, splice variation and other variations. Furthermore, ligation by transglutamimase factor XIII (cross-linking) adds to the complexity of the fibrin network. The structure and function of the fibrin network is in part determined by this natural variation in the fibrinogen molecule, with major effects from slice variation and cross-linking. This mini-review will discuss the direct effects of fibrinogen αEC and fibrinogen γ’ splice variation on clot structure and function and also discuss the additional role of fibrinogen γ’ as thrombomodulin II. Furthermore, the effects of cross-linking on clot function will be described. Splice variation and cross-linking are major determinants of the structure and function of fibrin and may therefore impact on diseases affecting bleeding, thrombosis and tissue repair

Root canal hydrophobization by dentinal silanization: Improvement of silicon-based endodontic treatment tightness

A new strategy to improve silicon-based endodontic treatment tightness by dentine hydrophobization is presented in this work: root dentine was silanized to obtain a hydrophobic dentine-sealer interface that limits fluid penetration. This strategy was based on the grafting of aliphatic carbon chains on the dentine through a silanization with the silane end groups [octadecyltrichlorosilane (OTS) and octadecyltriethoxysilane]. Dentine surface was previously pretreated, applying ethylenediaminetetraacetic acid and sodium hypochlorite, to expose hydroxyl groups of collagen for the silane grafting. Collagen fibers exposure after pretreatment was visible with scanning electron microscopy, and Fourier transform infrared (FTIR) spectroscopy showed their correct exposition for the silanization (amide I and II, with 1630, 1580, and 1538 cm⁻¹ peaks corresponding to the vibration of C=O and C--N bonds). The grafting of aliphatic carbon chains was confirmed by FTIR (peaks at 2952 and 2923 cm⁻¹ corresponding to the stretching of C--H bonds) and by the increasing of the water contact angle. The most efficient hydrophobization was obtained with OTS in ethyl acetate, with a water contact angle turning from 51° to 109°. Gas and liquid permeability tests showed an increased seal tightness after silanization: the mean gas and water flows dropped from 2.02 × 10⁻⁸ to 1.62 × 10⁻⁸ mol s⁻¹ and from 10.8 × 10⁻³ to 5.4 × 10⁻³ µL min⁻¹, respectively. These results show clear evidences to turn hydrophilic dentine surface into a hydrophobic surface that may improve endodontic sealing. Copyright © 2013 Wiley Periodicals, Inc